Serrapeptase HP™: What It Is, Why Enteric Coating Matters, and How It Supports Respiratory & Sinus Health
If you’ve ever gone down the “systemic enzyme” rabbit hole, you’ve probably seen serrapeptase come up a lot, especially in conversations around respiratory and sinus support. Today I’m breaking down Serrapeptase HP™, a high-potency serrapeptase supplement designed to support healthy fibrin and promote respiratory and sinus health, with one important feature: it’s enteric-coated.*
First: What is serrapeptase?
Serrapeptase (also called serrapeptidase, serratiopeptidase, or serratia peptidase) is a proteolytic enzyme, meaning it helps break down proteins.
It has a fascinating origin story: serrapeptase is derived from a bacterial species originally found in silkworm intestines. The bacterium Serratia marcescens produces serrapeptase to help the silkworm dissolve its cocoon and emerge as a moth during metamorphosis. Today, serrapeptase is produced through fermentation (Serratia grown in cultures), and the ingredient used here is suitable for vegetarians.
Why Serrapeptase HP™ stands out: the enteric coating
Here’s the issue with many serrapeptase products: they aren’t enteric-coated.
That matters because enzymes like serrapeptase can lose effectiveness when exposed to the highly acidic environment of the stomach. If the enzyme breaks down before it reaches the intestines, you may not get the intended activity.
Serrapeptase HP™ is enteric-coated, which helps it survive stomach acid and reach the intestines, supporting optimal absorption and helping the enzyme remain active.*
In other words: the coating is not just a “nice extra.” It’s a core reason this kind of supplement is formulated the way it is.
What “supports healthy fibrin” means
This product is positioned to support healthy fibrin.* Fibrin is a protein involved in normal clotting and tissue processes. When a supplement mentions fibrin support, it’s usually referring to supporting the body’s normal balance in protein breakdown pathways, which is one reason systemic enzymes are popular in wellness routines.
What it’s commonly used for
According to the product description, Serrapeptase HP™ is intended to support:
Respiratory health *
Sinus health *
Healthy fibrin *
Ingredients list (One capsule contains)
Active ingredient:
Enteric-Coated Serrapeptase† — 65 mg
Serrapeptase — 130,000 SPU
MAAC (methacrylic acid copolymer) — enteric coating
Other Ingredients: Hydroxypropyl methylcellulose (vegetable capsule), maltodextrin (from corn), silica.
Does Not Contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.
Caution + storage
Caution: If pregnant, nursing, or taking any medications, consult your healthcare practitioner before use. Keep out of reach of children.
Storage: Keep tightly closed in a cool, dry place.
My HealthMint take
If someone is specifically shopping for serrapeptase, I consider enteric coating a non-negotiable feature. Since enzymes are sensitive and stomach acid is harsh, the coating can make the difference between “looks good on the label” and “actually reaches the place it needs to be.” Serrapeptase HP™ is built with that in mind, and it delivers a clearly stated potency of 130,000 SPU per capsule.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Serrapeptase HP™ is a powerful systemic enzyme which supports respiratory and sinus health.* This formula is enteric-coated to survive the acidic conditions of the stomach, promoting optimal absorption.*
Serrapeptase – also known as serrapeptidase, serratiopeptidase and serratia peptidase – is a powerful proteolytic enzyme derived from a species of bacteria originally found in the intestine of silkworms. The bacterium, Serratia marcescens, produces the enzyme serrapeptase to enable the silkworm to dissolve its silken cocoon and emerge as a moth after metamorphosis. Serratia is now grown in cultures to produce serrapeptase by fermentation, and it is suitable for vegetarians.
Most serrapeptase brands on the market are not enteric-coated, which means they can lose a significant portion of their effectiveness in the acidic environment of the stomach. The enteric coating of our blend maximizes efficacy by allowing these sensitive enzymes to survive the acidic conditions of the stomach, allowing them to pass into the circulatory system and maintain high activity levels.
