Methyl Folate™ (5-MTHF): A Simple Guide to the Most Bioactive Form of Folate
Folate is often overlooked, yet it supports your body’s key functions, particularly cardiovascular and methylation pathways. That’s why I’m highlighting Methyl Folate™ (5-MTHF), made with Quatrefolic®, described as the most biologically active folate form designed for rapid absorption.*
What makes this form stand out is that it’s already methylated and metabolically active, meaning it’s ready for the body to use and doesn’t require additional conversion for absorption.*
What 5-MTHF actually is (and why “L-methylfolate” matters)
This product provides folate as (6S)-5-methyltetrahydrofolic acid, also known as 5-MTHF.
You may also hear 5-MTHF referred to as the “L” form. This means it’s the body’s usable, reduced form of folate.
Why folate matters for homocysteine and cardiovascular support
One of folate’s key jobs is supporting the conversion of homocysteine to methionine.* Homocysteine is an amino acid that the body naturally produces, and maintaining healthy homocysteine metabolism is often part of broader cardiovascular wellness support.
That’s why this supplement is positioned to support:
Healthy cardiovascular function *
Healthy homocysteine levels *
Key benefits
The most biologically active form of folate (5-MTHF) *
Supports healthy cardiovascular function *
Supports healthy homocysteine levels *
Ingredients list (One Capsule Contains)
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt)† — 1,360 mcg DFE
Other Ingredients: Microcrystalline cellulose, hydroxypropyl methylcellulose (vegetable capsule), stearic acid, magnesium stearate, silicon dioxide.
Does Not Contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.
Caution + storage
Caution: Keep out of reach of children.
Storage: Keep tightly closed in a cool, dry place.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
