L-5-MTHF: Active Folate for Methylation, Heart, and Brain Health
Folate, also known as vitamin B9, is essential for many processes in the body. But not all folate forms are equally effective. While folic acid is the common synthetic form used in fortified foods and many supplements, it must go through several conversions before becoming active in the body. For some people—especially those with certain genetic variations—this conversion is inefficient.
L-5-MTHF provides folate in its biologically active form, 5-methyltetrahydrofolate (5-MTHF), ready for the body to use without extra steps. This ensures reliable support for methylation, homocysteine metabolism, cardiovascular health, neurological function, and reproductive wellness.
Why Choose L-5-MTHF?
Bioactive form: L-5-MTHF is the circulating form of folate found naturally in the body.
Genetic considerations: Individuals with MTHFR gene variants may have reduced ability to convert folic acid into active folate, making L-5-MTHF a superior option.
High bioavailability: This product uses Quatrefolic®, a patented form of folate with superior solubility and stability.
Supports methylation: Methylation is a vital biochemical process that turns “switches” on and off in the body, influencing cardiovascular, neurological, detoxification, and reproductive health.
Key Benefits
Supports folate status
Promotes normal methylation
Helps regulate homocysteine metabolism
Contributes to cardiovascular, brain, detox, and reproductive health
Ingredients in L-5-MTHF
Each capsule provides:
Folate (as [6S]-5-methyltetrahydrofolate, Quatrefolic®) – available in 3 strengths:
850 mcg DFE
1,700 mcg DFE
8,500 mcg DFE
Other Features:
Uses a glucosamine salt form instead of calcium salt for increased bioavailability.
Patented Quatrefolic® form for stability and potency.
Recommended Use
Take 1 capsule daily, or as directed by your healthcare practitioner.
⚠️ Note: Do not exceed recommended intake or use long-term without medical supervision. Folate can mask vitamin B12 deficiency, so proper monitoring is important.
Final Thoughts
For individuals seeking reliable folate support—especially those with methylation challenges—L-5-MTHF offers a direct, highly bioavailable form of folate. By bypassing conversion steps, it ensures optimal support for cardiovascular, neurological, reproductive, and detoxification processes.
