BRF 45™: Advanced Vitamin K2 Support for Strong Bones and Healthy Arteries

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Bone health is vital at every stage of life, but it becomes especially important as we age. Both men and women face changes in bone strength due to hormonal shifts, with bone loss being particularly common during menopause and andropause. To help protect bone density and support arterial health, Designs for Health created BRF 45™, a powerful vitamin K2 formula.

What is BRF 45™?

BRF 45™ is an advanced supplement designed to support bone health, strength, and arterial integrity. It provides a clinically studied dose of 45 mg of vitamin K2 (as MK-4)—the most abundant and biologically active form of vitamin K2 in humans. Research shows that MK-4 plays a key role in supporting calcium metabolism, bone remodeling, and overall skeletal strength.

Why Vitamin K2 Matters

Vitamin K exists in two essential forms:

  • Vitamin K1: Found in leafy greens, it supports healthy blood clotting.

  • Vitamin K2 (as MK-4): Found in animal-based foods like grass-fed butter, full-fat cheese, eggs, and meats. K2 is critical for activating bone-building proteins and ensuring that calcium goes into the bones and teeth rather than depositing in the arteries.

Without adequate vitamin K2, calcium balance may be disrupted, potentially leading to weaker bones and stiff arteries.

Key Benefits of BRF 45™

  • Supports bone strength and density by helping bind calcium to the bone matrix

  • Promotes arterial elasticity and integrity for cardiovascular wellness

  • Helps maintain collagen and calcium content in bones

  • May benefit those at risk of bone loss or arterial stiffness

  • Provides support for individuals on certain medications that may increase the body’s demand for vitamin K

The Role of Geranylgeraniol (GG)

BRF 45™ also includes Geranylgeraniol (GG-Gold®), a natural building block for vitamin K2 production. GG enhances the body’s own ability to utilize K2 effectively, adding an extra layer of support for bone and arterial health.

Clean and Effective Formula

  • Delivered in softgels for optimal absorption

  • Includes both vitamin K1 and vitamin K2 (MK-4) for comprehensive support

  • Backed by clinically researched doses for effectiveness

Recommended Use

Take two softgels daily with meals (one with breakfast, one with lunch or dinner), or as directed by your healthcare provider.

⚠️ Important Note: If you are taking anticoagulant medications such as Coumadin or warfarin, consult your healthcare practitioner before use.

Final Thoughts

Bone strength and arterial health are deeply connected, and vitamin K2 plays a critical role in both. By combining clinically studied doses of MK-4 with GG for enhanced support, BRF 45™ helps ensure that calcium goes where it belongs—strengthening your bones and teeth—while protecting your arteries.

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